Chennai, 6th October 2025 – In a groundbreaking medical feat, Kauvery Hospital, Chennai, has successfully performed the world’s first transcatheter mitral valve replacement (TMVR) with an extended external wrap and atrialized implant via femoral vein access on an 83-year-old woman deemed “inoperable” by leading cardiac surgeons. The patient, who suffered from severe Mitral Valve dysfunction due to heavy Mitral Annular Calcification (MAC), had undergone radiotherapy to the chest twice in the past and was rejected for surgery by multiple hospitals due to her high-risk condition. Traditional open-heart or even minimally invasive surgical options were considered too dangerous. Youtube Video link 👇 MAC, a condition where calcium deposits harden the area around the mitral valve, poses serious challenges for both surgery and catheter-based interventions. The calcified "ring" makes it extremely difficult to securely place a new valve, increasing the risk of complications. To addres...