Madras Medical Mission Pioneers Dual Chamber Leadless Pacemaker Implants: Advancing the Future of Cardiac Care

Chennai, November 04, 2025: In a landmark achievement for cardiac care, Madras Medical Mission (MMM) successfully performed its first implantation of a true dual chamber leadless pacemaker, marking a significant milestone in heart rhythm management and electrophysiology. This cutting-edge procedure offers a minimally invasive alternative to traditional pacemakers, reducing risks of infection, discomfort, and recovery time.

The recipient, a 75-year-old man with complete heart block, had been experiencing dizziness and fatigue that limited his daily activities. Due to his high infection risk with conventional pacemakers, MMM’s electrophysiology team opted for the leadless pacemaker system as a safer, more advanced option.

Unlike traditional pacemakers that rely on leads and a surgical pocket, this dual chamber system involves two miniature, self-contained pacemakers—one in the right atrium and another in the right ventricle—each roughly one-tenth the size of a conventional device. These pacemakers communicate wirelessly to maintain synchronized, natural heart rhythms.

Dr. Ulhas Pandurangi, Senior Consultant and Head of Electrophysiology, said, “This represents a generational leap in cardiac pacing. By avoiding wires and surgical pockets, we reduce infection and lead-related complications while enhancing comfort and recovery. The system’s wireless synchronization and miniaturized design offer superior clinical outcomes.”

Dr. Ajit Mullasari, Chairman, Cardiology, added, “The device, known as the AVEIR DR system, is implanted via a catheter through a leg vein—no chest incision or scarring. The procedure typically takes under an hour, and most patients resume normal activities within a day.”

He also noted that MMM has already completed a second implantation in a 92-year-old patient, underscoring the hospital’s commitment to offering innovative and compassionate care.

The AVEIR DR pacemaker uses advanced implant-to-implant (i2i™) communication, ensuring precise, beat-to-beat synchronization between the heart’s chambers. This breakthrough marks a new era in pacing therapy, particularly beneficial for elderly or high-risk patients.

Dr. Anindya Ghosh, Consultant Cardiologist and Electrophysiologist, emphasized, “Leadless dual chamber pacing fundamentally changes how we treat complex rhythm disorders, especially in patients unsuitable for traditional devices.”

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